Transcranial Magnetic Stimulation (TMS)

The Kopala-Sibley research team is excited to announce that we have added a new optional component to the C-BRAID study called TMS!

What is TMS?

Transcranial magnetic stimulation (TMS) is a tool for studying brain function in humans safely and non-invasively. TMS is a safe and painless brain stimulation done by holding a magnetic coil above your head to deliver a small pulse. The practice of TMS has been in use for over thirty-five years and has been approved by both the Food and Drug Association (FDA) and Health Canada. TMS is based on the principles of electromagnetic induction to induce an electrical current inside the brain.

About This Study

By measuring electrical signals in the brain using electroencephalography (EEG) some features of brain function differentiate individuals with major depression and those without. Yet, we do not yet know whether these are cause or effect in major depression, and, as a result, we do not know whether EEG features can be used to identify individuals at high risk of developing major depression. As such, we want to use transcranial magnetic stimulation (TMS) to find out which regions of the brain are implicated in major depression. If you choose to participate, you and your child's TMS will happen on the same day as your child's MRI and EEG scans. It will take approximately an extra 2 hours total for both you and your child to complete the TMS portion.